The science behind IQOS

IQOS is a combination between science and technology.

Let’s look at the key scientific evidence related to IQOS

IQOS has extensive and robust clinical evidence* showing that using IQOS presents less risk to your health than continuing to smoke. Did you know that IQOS tobacco heating technology is based on scientific research and testing? Numerous studies have been carried out to evaluate the product, including 18 non-clinical and 10 clinical trials.

Important information: IQOS is not risk-free and provides nicotine, which is addictive.

*Source: Based on the totality of evidence available for IQOS in comparison with continuing to smoke. See Important Information.
PMI building in Switzerland
A burning cigarette and a bronze IQOS holder next to each other

Why is heating better

Technology – the world revolves around it. Over the years, it has radically changed our lives for the better. The way we work, the way we communicate, the way we travel.
By combining science and technology is how we developed a better alternative to continued smoking.
IQOS is a better choice for those adult smokers, who would otherwise continue to smoke.

The burning of tobacco emits high amounts of harmful chemicals. IQOS heats the tobacco stick instead of burning it.

IQOS ILUMA SMARTCORE INDUCTION™ technology prevents tobacco stick from burning, which means it significantly reduces the number and level of harmful chemicals emitted compared to cigarette smoke.


Important information: IQOS is not risk-free.

Heating technology

Cigarettes burn tabacco, reaching high temperatures, and producing ash, tar, and smoke with high number and levels of harmful chemicals.

Cigarette smoke is a complex mixture of over 6,000 chemical substances, around 100 of which have been linked to smoking-related diseases by public health authorities.

IQOS ILUMA SMARTCORE INDUCTION SYSTEMTM technology heats the tobacco stick to a lower temperature, ensuring that combustion. Because there is no combustion, IQOS does not produce smoke. It generates a vapor that brings you experience with 95% less harmful chemicals compared to cigarette smoke.*

Important information: It does not necessarily equal a 95% reduction in risk. IQOS is not risk-free.
*“95% less” represents the average reduction in levels of the 9 chemicals recommended for reduction in cigarette smoke by the World Health Organization, which do not include nicotine. See Important Information.
A burning cigarette and a bronze IQOS holder next to each other

Cigarettes produce tar – IQOS doesn’t

Tar is the residue from smoke after a cigarette is burned. IQOS does not produce tar because it heats the sticks instead of burning it. It generates an aerosol residue that is fundamentally different from tar and consists of significantly lower levels of harmful chemicals.*

Switching completely to IQOS is less harmful than continuing to smoke.**
Important information: The absence of tar does not mean that IQOS is risk free. IQOS provides nicotine which is addictive.
*Reductions in levels of the 9 harmful chemicals the World Health Organization recommends to reduce in cigarette smoke, which do not include nicotine. See Important Information.
**Source: Based on the totality of evidence available for IQOS in comparison with continuing to smoke. See Important Information.
Close up of a residue sample card.

Vapor vs smoke

Switching completely to IQOS is less harmful than continuing to smoke.* To demonstrate this, we conducted a comprehensive assessment program that included 10 clinical studies on aerosol chemistry (as well as data from 18 non-clinical studies), and involved thousands of participants in the US, Japan, UK and Poland. Evidence demonstrates that switching completely to IQOS, while not risk-free, presents less risk of harm compared with continuing to smoke cigarettes.


Important information: IQOS is not risk-free and provides nicotine, which is addictive.

*Source: Based on the totality of evidence available for IQOS in comparison with continuing to smoke. See Important Information.

IQOS emits less harmful chemicals than cigarettes.

Cigarettes burn tobacco, which produces high amounts of carbon monoxide. IQOS doesn’t burn the sticks, producing on average 98% less carbon monoxide (CO) and significantly lower levels of other harmful chemicals compared to cigarettes.*
Important information: This does not mean a 98% reduction in risk, and carbon monoxid is only one of many harmful chemicals in cigarette smoke. IQOS is not risk free, and delivers nicotine which is addictive.
*Reductions in levels of the 9 harmful chemicals the World Health Organization recommends to reduce in cigarette smoke, which do not include nicotine. See Important Information.

Indoor Air Quality

Indoor Air Quality (“IAQ”) refers to the air quality inside buildings, generally based on the principle of ensuring the health and comfort of the occupants. Temperature, humidity and contaminants are some of the factors that can affect the indoor air quality. But, human presence and activities such as cooking, cleaning or smoking have been proven to have considerable impact.

To enhance our knowledge and understanding the impact of IQOS on indoor air quality we conducted studies simulating “real-world” conditions in an environmentally controlled room. Our testing methods are validated, and ISO accredited.

Our study shows that, because IQOS does not burn tobacco and it does not generate smoke and it drastically reduces levels of harmful chemicals like carbon monoxide, it does not negatively impact indoor air quality.

This means that the few compounds we nevertheless detected were found at very low concentrations and far below the maximum exposure levels defined in existing air quality guidelines.
Illustration contrasting effects of cigarette smoke versus IQOS on indoor air quality.

Exclusive usage of IQOS

Our studies' participants who completely switched to IQOS also report that IQOS provides comparable levels of satisfaction as cigarettes.*
IQOS is not risk-free and delivers nicotine, which is addictive.
* 3-month clinical study conducted in US and Japan with 160 adult smokers each, under near real-world conditions.
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Stellar blue IQOS 3 DUO holder lying on an autumnal leaf
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All information about tobacco sticks that is stated or displayed in the materials applies to all SMARTCORE STICKS™ sticks. IQOS ILUMA is designed to be used only with SMARTCORE STICKS™. Do not use IQOS ILUMA and SMARTCORE STICKS™ with previous IQOS generations, as this may cause damage to your device. Do not ingest or disassemble SMARTCORE STICKS™. This product contains a sharp metal part which can cause serious injury if swallowed. Keep out of reach of children and pets. See